My rebuttal precedes me: the "magic bullet" theory, viz. kennedy. Totally debunked. No further explanation on my part is necessary. But I'll summarize the key point...
Bullets may yaw, tumble and/or ricochet off bone when shot into animals. No bullet radically changes trajectory numerous times before exiting/stopping in its path, like a rubber ball inside the body, as your comments illustrate, laughably.
Nothing has changed. The popular misconception of the .22 rimfire as some "best known secret" for self-defense is an old one, and a potentially deadly one...to its adherents. I only wish I had the statistics here to back that up, though they should prove impressively true.