DUF1220
The Genetic Key to Human Intelligence May Lie in a Fragment Called DUF1220
https://www.inverse.com/article/1029...called-duf1220
DUF1220 copy number is linearly associated with increased cognitive function as measured by total IQ and mathematical aptitude scores.
https://www.ncbi.nlm.nih.gov/pubmed/25287832
Quote:
Among primate lineages, there is a high correlation between DUF1220 copy number (the highest copy number, >270, was found in Homo sapiens [human and Neanderthal]) and increased brain size (R2 = 0.98; p = 1.8 × 10−6) (Figure S4A), as well as an increased number of cortical neurons
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511999/